Man vs. nature

When are people going to realize that man can not win? We have done so much damage and chaos to this planet to the point where we now want to make changes to protect it and maintain it. Nature is a topic and a thing not to quarrel with. It all started with the Industrial Revolution. New technologies came about and advances in everyday life which is great. Half of the things that we think that we need, we don't need. We are constantly trying to control life. Stem cell research is great to cure people with certain illnesses and diseases. What happened to nature taking it's course? What more can we do to to alter the changes in life?